What Is Y Chromosome Microdeletion Test?

The Y Chromosome Microdeletion Test is a highly specialized genetic test that helps identify missing segments (microdeletions) on the Y chromosome, particularly in regions essential for sperm production. These deletions often lead to male infertility, such as azoospermia (no sperm) or oligospermia (low sperm count).

The test focuses on detecting deletions in the AZF regions (AZFa, AZFb, AZFc) of the Y chromosome, which are linked to non-obstructive infertility in men.

Why Choose Y Chromosome Microdeletion Test In Dubai?

? Detects Hidden Genetic Causes Of Male Infertility
? Supports Personalized Fertility Treatment Plans
?‍⚕️ Recommended By Fertility Clinics And Urologists
? Available In Top Genetic Labs Across Dubai
⚡ Quick Turnaround Time – 5 To 7 Working Days
✅ Non-Invasive And Highly Accurate

Who Should Consider This Test?

✔️ Men Diagnosed With Azoospermia (No Sperm In Semen)
✔️ Men With Severely Low Sperm Count (Oligospermia)
✔️ Couples Facing Unexplained Infertility
✔️ Individuals Planning IVF Or ICSI Treatments
✔️ Men With A Family History Of Infertility Or Genetic Disorders

Benefits Of Y Chromosome Microdeletion Testing

✨ Identifies Genetic Cause Of Infertility In Men
✨ Helps In Selecting The Right Fertility Treatment (Like IVF/ICSI)
✨ Provides Valuable Insights For Genetic Counseling
✨ Simple, Non-Invasive DNA-Based Test
✨ Reduces Trial-And-Error In Infertility Treatment

Procedure Of The Test

? Sample Collection

• A blood sample is collected from the patient in a sterile environment.

? DNA Extraction

• DNA is extracted from the white blood cells in the sample.

? PCR Amplification

• Specific regions of the Y chromosome (AZFa, AZFb, AZFc) are amplified using polymerase chain reaction (PCR).

? Microdeletion Analysis

• The PCR results are analyzed to detect any missing genetic material in the AZF regions.

? Reporting

• A clear, easy-to-understand report is shared with the patient and their specialist, indicating whether a microdeletion is present and its location.

Methodology Of Test

The Y Chromosome Microdeletion Test uses PCR-based molecular diagnostics to detect small deletions in specific regions of the Y chromosome.

? Key Methodology Highlights:

• Targeted Regions: AZFa, AZFb, AZFc

• Technology: Multiplex PCR or Real-Time PCR

• Sample Type: Blood

• Accuracy: >99% in detecting clinically relevant deletions

• Turnaround Time: Typically 5 to 7 working days

• Clinical Use: Identifies suitability for assisted reproductive technologies like TESE, IVF, ICSI

This method ensures high sensitivity and is internationally recommended for infertility assessments.

Conclusion

The Y Chromosome Microdeletion Test is a critical step in understanding genetic causes of male infertility. Whether you’re planning a family, undergoing fertility treatment, or seeking answers to unexplained sperm issues, this test offers precision, clarity, and direction.