The Urine Immunofixation Test (Immuno Electrophoresis) is a high-sensitivity diagnostic test that detects monoclonal proteins (M-proteins) in urine. These proteins are commonly associated with plasma cell disorders such as multiple myeloma, light chain disease, and monoclonal gammopathy. This test is especially important when symptoms are present but not confirmed by blood tests alone.

? Test Turnaround Time: 5–7 Days
? Sample Required: 24-hour or random urine sample
? Clinical Significance: Detects presence and type of Bence Jones proteins

? Type Of Test

• Category: Protein Electrophoresis / Immunodiagnostic

• Sample Type: Urine (usually 24-hour collection preferred)

• Usage: Identify abnormal monoclonal proteins (M-proteins) linked to plasma cell malignancies

⚙️ Methodology Of Test

• Test Method: Immunofixation Electrophoresis (IFE)

• Principle: Urine proteins are separated using electrophoresis and then treated with antibodies specific to immunoglobulins (IgG, IgA, IgM, light chains κ & λ). This reveals monoclonal bands, if present.

• Result: Identifies type and quantity of monoclonal immunoglobulin

• Sensitivity: Higher sensitivity than standard electrophoresis

? Why This Test Is Important In Dubai

• Increasing cases of multiple myeloma and related conditions among aging and high-risk populations

• Helps detect Bence Jones proteins, often missed in blood tests

• Vital for early detection of malignancies or monoclonal gammopathies

• Supports advanced diagnostics in Dubai’s top-tier healthcare system

? Key Benefits
✅ Detects early signs of plasma cell disorders
✅ Essential for diagnosing light chain multiple myeloma
✅ More sensitive than routine urine protein tests
✅ Helps track disease progression and treatment effectiveness
✅ Supports decision-making in hematology and oncology

? Who Should Take This Test?

• Patients with unexplained fatigue, bone pain, or recurrent infections

• Individuals with abnormal serum protein levels

• People under evaluation for multiple myeloma or MGUS

• Patients with chronic kidney disease of unknown cause

• Individuals with known or suspected plasma cell neoplasms

? FAQs – Frequently Asked Questions

Q1. What does the Urine Immunofixation Test detect?
It detects monoclonal (M) proteins in urine, which can be signs of multiple myeloma or related disorders.

Q2. How is the sample collected?
A 24-hour urine sample is preferred, but sometimes a random urine sample is used.

Q3. Do I need any preparation before this test?
No special preparation is required. However, your doctor may ask you to avoid certain medications.

Q4. Is this test painful?
No, it is a non-invasive urine test.

? Additional Highlights
? Used along with serum protein electrophoresis (SPEP)
? Helps confirm Bence Jones proteinuria
? Often repeated during cancer monitoring and treatment
? Recommended for all patients under suspicion for hematological malignancy

? Conclusion
The Urine Immunofixation (Immuno Electrophoresis) Test is a vital diagnostic tool for accurately identifying monoclonal proteins and diagnosing serious plasma cell disorders like multiple myeloma. In a city like Dubai, where early detection and precision medicine are critical, this test ensures timely and targeted treatment.

✨ Detect disease early. Act confidently.
? Book your Urine Immunofixation Test in Dubai today!