What Is Prothrombin Mutation Analysis?

The Prothrombin Mutation Analysis is a genetic test used to detect the G20210A mutation in the F2 (Prothrombin) gene, which can increase the risk of abnormal blood clot formation (thrombophilia). This inherited condition is linked to deep vein thrombosis (DVT), pulmonary embolism, and complications in pregnancy, including miscarriage.

This test is essential for individuals with a personal or family history of blood clots, or those undergoing surgery, hormone therapy, or fertility treatments, where clotting risks are elevated.

Why Choose Prothrombin Mutation Test In Dubai?

? Detects Inherited Risk Of Dangerous Blood Clots
? Helps In Prevention Of DVT, PE, And Pregnancy Loss
? Performed In Accredited DNA Labs In Dubai
? Highly Accurate PCR-Based Genetic Screening
⚡ Fast Reporting – Results Within 5 To 7 Working Days
?‍⚕️ Recommended By Hematologists And OBGYNs

Who Should Consider This Test?

✔️ Individuals With A History Of Unexplained Blood Clots
✔️ Women With Recurrent Pregnancy Loss Or Fertility Issues
✔️ Patients Planning Surgery Or Hormonal Treatments
✔️ Those With A Family History Of Thrombophilia Or Stroke
✔️ Anyone At Risk For Pulmonary Embolism Or DVT

Benefits Of Prothrombin Mutation Analysis

✨ Early Detection Of A Life-Threatening Clotting Disorder
✨ Enables Proactive Preventive Measures
✨ Informs Doctors On Use Of Blood Thinners Or Anticoagulants
✨ Personalized Risk Management For Pregnancy & Surgery
✨ Supports Family Genetic Counseling

Procedure Of The Test

? Sample Collection

• A simple blood or saliva sample is collected in a sterile container.

? DNA Extraction & Amplification

• DNA is extracted from the sample and the F2 gene is amplified using PCR technology.

? Mutation Detection

• The lab checks for the presence of the G20210A mutation (heterozygous or homozygous).

? Result Interpretation

• A comprehensive report outlines your genetic status and potential thrombosis risk.

Methodology Of Test

The Prothrombin Mutation Analysis is performed using Real-Time PCR (Polymerase Chain Reaction) techniques to detect the G20210A point mutation in the F2 gene.

? Key Method Highlights:

• Gene Analyzed: F2 (Prothrombin)

• Mutation Detected: G20210A

• Technology Used: Real-Time PCR

• Sample Type: Blood or Saliva

• Turnaround Time: 5 to 7 working days

• Accuracy: >99% for detecting clinically relevant mutations

• Use Cases: Thrombophilia screening, fertility risk analysis, cardiovascular risk prevention

This test is highly reliable and used globally in preventive hematology and reproductive care.

FAQ Section

What is the G20210A mutation?
It is a change in the prothrombin (F2) gene that increases the risk of forming abnormal blood clots in veins.

Can this mutation cause pregnancy complications?
Yes, it has been associated with recurrent miscarriages, preeclampsia, and blood clots during pregnancy.

How do I know if I need this test?
If you or a family member has had DVT, stroke, pulmonary embolism, or pregnancy loss, testing may be recommended.

Is the test painful or invasive?
No. The test only requires a blood or saliva sample, and is completely safe and non-invasive.

How long does it take to get results?
Results are usually ready within 5 to 7 business days after sample collection.

Will this test help in planning pregnancy or surgery?
Absolutely. Knowing your clotting risk in advance helps your doctor plan preventive treatments before pregnancy or major procedures.

Conclusion

The Prothrombin Mutation Analysis is a vital tool in identifying genetic risk for thrombophilia, enabling early preventive strategies that could be life-saving. Whether you're planning surgery, starting a family, or have a personal/family history of clots, this test provides clear answers and peace of mind.