? What Is The Oncomine MDS Panel Test?
The Oncomine Myelodysplastic Syndrome (MDS) Panel is a specialized next-generation sequencing (NGS) test that detects mutations in genes linked to MDS and other bone marrow failure syndromes. This test supports hematologists in diagnosing MDS, evaluating disease progression, and making informed decisions on targeted therapies or bone marrow transplant options.

? Why Do People In Dubai Choose This Test?

✔️ Detects mutations in over 40 MDS-related genes like TP53, TET2, ASXL1, SF3B1, DNMT3A, RUNX1
✔️ Enables early and accurate diagnosis of MDS
✔️ Assists in identifying prognostic risk categories
✔️ Supports clinical decision-making for personalized treatment
✔️ Available at top-tier hospitals and diagnostics labs across Dubai

? Methodology Of The Test

1. Sample Collection:
   A blood sample or bone marrow aspirate is collected at a certified medical facility.

2. DNA Extraction:
   Genomic DNA is extracted from the sample to identify somatic mutations.

3. NGS Sequencing:
   The DNA undergoes high-throughput sequencing to detect point mutations, insertions, deletions, and copy number variations in MDS-associated genes.

4. Bioinformatics Interpretation:
   Advanced software tools are used to interpret the results and match them to clinical guidelines.

5. Report Generation:
   A comprehensive report is issued within 10–14 working days, highlighting mutations, clinical impact, and therapeutic options.

? When Should You Take This Test?

• If you have unexplained anemia, fatigue, or low blood counts
• After a bone marrow biopsy suggesting dysplastic changes
• When MDS or another clonal hematologic disorder is suspected
• To guide therapy or assess eligibility for a bone marrow transplant
• As part of a risk stratification strategy before starting treatment

? Cost Of The MDS Panel In Dubai

The test usually ranges between AED 3,500 – AED 7,000, depending on the healthcare provider, gene coverage, and whether genetic counseling is included.

?‍♀️ Frequently Asked Questions (FAQ)

Q1: What is MDS and why is genetic testing important?
MDS is a group of disorders caused by poorly formed or dysfunctional blood cells. Genetic testing helps to confirm diagnosis, classify risk, and guide treatment.

Q2: Can this test predict progression to leukemia?
Yes, it can detect mutations associated with higher risk of transformation to acute myeloid leukemia (AML).

Q3: Is a bone marrow sample always required?
In some cases, a blood sample is sufficient, but for full accuracy, especially in early-stage disease, a bone marrow sample is often preferred.

Q4: Who should take this test?
Anyone with abnormal blood counts, suspected MDS, or a family history of hematologic malignancies should consider this test under medical advice.

Q5: Are the results confidential?
Absolutely. Results are handled with strict medical confidentiality in accordance with UAE healthcare regulations.

✅ Conclusion
The Oncomine Myelodysplastic Syndrome (MDS) Panel is an essential tool in the accurate diagnosis and management of MDS and related disorders. With comprehensive genetic insights, doctors in Dubai can design tailored treatment plans, improving patient outcomes and quality of life. If you or a loved one is undergoing evaluation for unexplained blood disorders or MDS, this test can provide the clarity and direction you need. Book your test today with a trusted healthcare provider in Dubai.